Complete blood count with Differential (CBC with DIFF): Red Cell Distribution Width (RDW)

Tags

alcohol, anemia, band neutrophils, bands, basophil, cancer, CBC, CBC with diff, CBC with differential, Chronic disease, Elevated RDW, eosinophil, Folate deficiency, Hydroxyurea, Imuran, infection, inflammation, iron deficiency, leukemia, liver disease, lymphocytes, lymphoma, malignancy, mcv, methotrexate, monocytes, Multiple myeloma, Myelodysplastic syndrome, neutrophil, Renal failure, Sickle cell Anemia, Thalassemia, Toxins, vitamin b12

Red Cell Distribution Width (RDW) measures the variability in the size of red blood cells. This parameter can help distinguish the various causes of anemia along with Mean corpuscular volume (MCV). With the addition of RDW, Mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) are no longer clinically used because of their limitations.

MCV is elevated (greater than 96) in:
– Vitamin B12 deficiency (Elevated RDW)
– Folate deficiency (Elevated RDW)
– Medications: Methotrexate, Imuran, Hydroxyurea (Normal RDW)
– Alcohol (Normal RDW)
– Liver disease (Elevated RDW)
– Multiple myeloma (Elevated RDW)
– Myelodysplastic syndrome (Elevated RDW)

MCV is normal (Between 80-96):
– Chronic disease (Elevated RDW)
– Renal failure (Elevated RDW)
– Sickle cell Anemia (Elevated RDW)
– Early Vitamin B12 and iron deficiency or mixed deficiencies (Elevated RDW)

MCV is low (less than 80) in:
– Iron deficiency (Elevated RDW)
– Toxins and drugs (Normal RDW)
– Thalassemia (Normal RDW)
– Myelodysplastic Syndrome (Elevated RDW)

Complete blood count with Differential (CBC with DIFF): Mean Corpuscular Hemoglobin (MCH)

Tags

alcohol, anemia, band neutrophils, bands, basophil, cancer, CBC, CBC with diff, CBC with differential, Chronic disease, Elevated RDW, eosinophil, Folate deficiency, Hydroxyurea, Imuran, infection, inflammation, iron deficiency, leukemia, liver disease, lymphocytes, lymphoma, malignancy, mcv, methotrexate, monocytes, Multiple myeloma, Myelodysplastic syndrome, neutrophil, Renal failure, Sickle cell Anemia, Thalassemia, Toxins, vitamin b12

Mean Corpuscular Hemoglobin (MCH) measures the average amount of Hemoglobin per single red blood cell. It was used in the past to determine the cause of anemia. But because of its limitations, Mean Corpuscular Volume or MCV along with Red Cell Distribution Width (RDW) have replaced MCH as means of determining the cause of anemia. These are outlined below:

MCV is elevated (greater than 96) in:
– Vitamin B12 deficiency (Elevated RDW)
– Folate deficiency (Elevated RDW)
– Medications: Methotrexate, Imuran, Hydroxyurea (Normal RDW)
– Alcohol (Normal RDW)
– Liver disease (Elevated RDW)
– Multiple myeloma (Elevated RDW)
– Myelodysplastic syndrome (Elevated RDW)

MCV is normal (Between 80-96):
– Chronic disease (Elevated RDW)
– Renal failure (Elevated RDW)
– Sickle cell Anemia (Elevated RDW)
– Early Vitamin B12 and iron deficiency or mixed deficiencies (Elevated RDW)

MCV is low (less than 80) in:
– Iron deficiency (Elevated RDW)
– Toxins and drugs (Normal RDW)
– Thalassemia (Normal RDW)
– Myelodysplastic Syndrome (Elevated RDW)

Complete blood count with Differential (CBC with DIFF): Mean Corpuscular Hemoglobin Concentration (MCHC)

Tags

alcohol, anemia, band neutrophils, bands, basophil, cancer, CBC, CBC with diff, CBC with differential, Chronic disease, Elevated RDW, eosinophil, Folate deficiency, Hydroxyurea, Imuran, infection, inflammation, iron deficiency, leukemia, liver disease, lymphocytes, lymphoma, malignancy, mcv, methotrexate, monocytes, Multiple myeloma, Myelodysplastic syndrome, neutrophil, Renal failure, Sickle cell Anemia, Thalassemia, Toxins, vitamin b12

Mean Corpuscular Hemoglobin Concentration (MCHC) measures the average concentration of hemoglobin per red blood cell. It was used in the past to determine the cause of anemia. But because of its limitations, Mean Corpuscular Volume or MCV along with Red Cell Distribution Width (RDW) have replaced MCHC as means of determining the cause of anemia. These are outlined below:

MCV is elevated (greater than 96) in:
– Vitamin B12 deficiency (Elevated RDW)
– Folate deficiency (Elevated RDW)
– Medications: Methotrexate, Imuran, Hydroxyurea (Normal RDW)
– Alcohol (Normal RDW)
– Liver disease (Elevated RDW)
– Multiple myeloma (Elevated RDW)
– Myelodysplastic syndrome (Elevated RDW)

MCV is normal (Between 80-96):
– Chronic disease (Elevated RDW)
– Renal failure (Elevated RDW)
– Sickle cell Anemia (Elevated RDW)
– Early Vitamin B12 and iron deficiency or mixed deficiencies (Elevated RDW)

MCV is low (less than 80) in:
– Iron deficiency (Elevated RDW)
– Toxins and drugs (Normal RDW)
– Thalassemia (Normal RDW)
– Myelodysplastic Syndrome (Elevated RDW)

Complete blood count with Differential (CBC with DIFF): Mean Corpuscular Volume (MCV)

Tags

alcohol, anemia, band neutrophils, bands, basophil, cancer, CBC, CBC with diff, CBC with differential, Chronic disease, Elevated RDW, eosinophil, Folate deficiency, Hydroxyurea, Imuran, infection, inflammation, iron deficiency, leukemia, liver disease, lymphocytes, lymphoma, malignancy, mcv, methotrexate, monocytes, Multiple myeloma, Myelodysplastic syndrome, neutrophil, Renal failure, Sickle cell Anemia, Thalassemia, Toxins, vitamin b12

Mean Corpuscular Volume (MCV) measures the volume of red blood cells using hematocrit and red blood cell count. It is indication of the size of the red blood cells. Normal range is between 80 and 96 depending on the individual laboratory.

MCV is used along with Red Cell Distribution Width (RDW) in order to determine the cause of anemia. With the addition of RDW, Mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) are no longer clinically used because of their limitations.

MCV is elevated (greater than 96) in:
– Vitamin B12 deficiency (Elevated RDW)
– Folate deficiency (Elevated RDW)
– Medications: Methotrexate, Imuran, Hydroxyurea (Normal RDW)
– Alcohol (Normal RDW)
– Liver disease (Elevated RDW)
– Multiple myeloma (Elevated RDW)
– Myelodysplastic syndrome (Elevated RDW)

MCV is normal (Between 80-96):
– Chronic disease (Elevated RDW)
– Renal failure (Elevated RDW)
– Sickle cell Anemia (Elevated RDW)
– Early Vitamin B12 and iron deficiency or mixed deficiencies (Elevated RDW)

MCV is low (less than 80) in:
– Iron deficiency (Elevated RDW)
– Toxins and drugs (Normal RDW)
– Thalassemia (Normal RDW)
– Myelodysplastic Syndrome (Elevated RDW)